Biophysical characteristics of gap junctions in vascular wall cells: implications for vascular biology and disease
نویسندگان
چکیده
منابع مشابه
Biophysical characteristics of gap junctions in vascular wall cells: implications for vascular biology and disease.
The role gap junction channels play in the normal and abnormal functioning of the vascular wall is the subject of much research. The biophysical properties of gap junctions are an essential component in understanding how gap junctions function to allow coordinated relaxation and contraction of vascular smooth muscle. This study reviews the properties thus far elucidated and relates those proper...
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Gap junctions between vessel wall cells provide a pathway for the intercellular exchange of ions and small molecules. Pure cultures of microvascular and macrovascular endothelial and smooth muscle cells, vascular pericytes, and several nonvascular cell lines were tested for junctional communication by fluorescent dye transfer. All of the vascular wall cells were capable of dye transfer. Since g...
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ژورنال
عنوان ژورنال: Brazilian Journal of Medical and Biological Research
سال: 2000
ISSN: 0100-879X
DOI: 10.1590/s0100-879x2000000400007